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Construction of a shared system-based real-world clinical research system

Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 382-388 doi: 10.1007/s11684-014-0368-5

Abstract:

Hubei Provincial Hospital of Traditional Chinese Medicine established research outpatient clinicsClinical Research Base and to the construction of the National Traditional Chinese Medicine Treatmentand Clinical Research Information Sharing System.,” these clinics explored the mode of constructing research outpatient clinics from the aspectsof clinical research, health management, and characteristics diagnosis and treatment.

Keywords： clinical research     shared system     real world     research outpatient clinic     research hospital    

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therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 827-858 doi: 10.1007/s11684-022-0948-8

Abstract: Infertility is experienced by 8%–12% of adults in their reproductive period globally and has become a prevalent concern. Besides routine therapeutic methods, stem cells are rapidly being examined as viable alternative therapies in regenerative medicine and translational investigation. Remarkable progress has been made in understanding the biology and purpose of stem cells. The affected pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) are further studied for their possible use in reproductive medicine, particularly for infertility induced by premature ovarian insufficiency and azoospermia. Accordingly, this study discusses current developments in the use of some kinds of MSCs such as adipose-derived stem cells, bone marrow stromal cells, umbilical cord MSCs, and menstrual blood MSCs. These methods have been used to manage ovarian and uterine disorders, and each technique presents a novel method for the therapy of infertility.

Keywords： infertility     stem cell therapy     mesenchymal stem cells     pluripotent stem cells    

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targeted therapy of gynecological malignant tumors: the development and challenge, from laboratory to clinic

Pengming SUN PhD, MD , Jalid SEHOULI PhD, MD , Lihui WEI BM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 256-264 doi: 10.1007/s11684-009-0052-3

Abstract: In this article, we systematically review the current targeted therapeutic trials running in clinic.

Keywords： target therapy     gynecologic malignant tumors     clinical trail     molecular medicine    

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A Clinic Study of Testosterone Propionate Treatmemt in Patients With Unstable Angina

Ma Jianfang,Zeng Aiping,Xie Dehui,Qiu Fengying,Zhang Ning,Chen Hong

Strategic Study of CAE 2003, Volume 5, Issue 4,   Pages 70-72

Abstract:

To investigate effects of testosterone propionate on patients with unstable angina, testosterone propionate (50mg, im) was given to 48 patients with unstable angina (test group), twice a week for 12 weeks. A group of patients with unstable angina were treated conventionally as a control. Clinical symptoms were evaluated and level of blood biochemistry was monitored before and after treatment. A dramatic improvement in clinical symptoms was observed in 46 out of 48 patients (96%) in the test group, demonstrating significant differences between the test and the control group (P＜0.01). In addition, the level of TC, LDL, CRP and TG reduced significantly and HDL - C increased slightly in the test group. However, no such changes were observed in the control group. A conclusion can be drawn that testosterone propionate can significantly improve clinical symptoms and blood biochemistry level in the patients with unstable angina, probably through modulating lipid metabolism, reducing inflammation response, and dilating blood vessel.

Keywords： unstable angina     testosterone propionate    

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Clinical acupuncture research in the West

Xianze Meng, Shifen Xu, Lixing Lao

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 134-140 doi: 10.1007/s11684-011-0135-9

Abstract: rapidly become part of mainstream medicine in the West, where new developments in acupuncture clinical researchAlthough challenges and difficulties remain, the acupuncture research community has matured and its pastexperience may lead to even better methods and more innovative research.

Keywords： acupuncture     clinical research     research methodology     the West    

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Do civil engineering fronts emerge from interdisciplinary research?

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 1,   Pages 1-9 doi: 10.1007/s11709-022-0929-7

Abstract: Interdisciplinary research is considered a source of innovativeness and creativity, serving as a keyThe aim of this study is to quantitatively establish the connection between interdisciplinary researchand the research fronts that have recently emerged in civil engineering.The degree of interdisciplinarity of the research fronts was measured by developing metrics from bibliographicAs indicated by the consistent increase in the metrics of interdisciplinarity over time, research fronts

Keywords： interdisciplinary research     research front     bibliographic analysis    

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Integrating operations research into green logistics: A review

Frontiers of Engineering Management   Pages 517-533 doi: 10.1007/s42524-023-0265-1

Abstract: Operations research provides a means to balance environmental concerns and costs, thereby enhancing theThis paper presents a comprehensive review of studies integrating operations research into green logisticsThe reviewed studies were categorized into five main research directions: Green waste logistics, theThe review concludes by outlining suggestions for further research that combines green logistics andoperations research, with particular emphasis on investigating the long-term effects of the pandemic

Keywords： green logistics     operations research     environment     literature review    

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Numerical simulation and experimental research on the wheel brush sampling process of an asteroid sampler

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11465-022-0732-0

Abstract: This research proposes the structural optimization design and motor selection of a wheel brush asteroid

Keywords： asteroid sampling     wheel brush sampler     discrete element method     parameter calibration     experimental research    

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The fundamental theory of traditional Chinese medicine and the consideration in its research strategy

Zhenji Li, Chunbo Xu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 208-211 doi: 10.1007/s11684-011-0126-x

Abstract: It suggests that when the research strategy of TCM theory is designed, the core theory of TCM shouldbe emphasized on the theoretical research on TCM original thinking theory, TCM theory, Chinese materiaResearchers and practitioners should ensure that the basic research on TCM theory is based on clinicalpractice, research methods (both traditional and contemporary) are exploited, and methodological innovation

Keywords： fundamental theory     traditional Chinese medicine     research strategy    

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Recent progress in hydrodynamic characteristics research and application of annular centrifugal extractors

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 6,   Pages 854-873 doi: 10.1007/s11705-022-2156-0

Abstract: More recently, research on hydrodynamic behavior and structural optimization has received widespreadHence, this paper reviews research progress regarding ACE in terms of hydrodynamic characteristics and

Keywords： annular centrifugal extractor     hydrodynamic characteristics     structure optimization     the latest application    

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HIGHLIGHTS OF THE SPECIAL ISSUE ON “HORTICULTURE RESEARCH FOR GREEN AND SUSTAINABLE DEVELOPMENT” EDITORIAL

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2, doi: 10.15302/J-FASE-2021396

Abstract: Horticultural research mainly focuses on breeding, cultivation and postharvest production related biologicalAlso, recent research on the exploitation and utilization of short-juvenile germplasm, like mini-citrus

Considering the rapid progress of horticulture research and its indispensable contribution toIts research findings cover QTL mapping and key gene mining for maesil weeping traits ( HTML PDF Collect

CAPEES and FESE journal: Together to serve the environmental research community

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 5, doi: 10.1007/s11783-022-1546-3

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The Effect of TRIZ on Research Institute Innovation

He Liu,Qing-hai Yang,Xu Jin

Frontiers of Engineering Management 2014, Volume 1, Issue 4,   Pages 385-389 doi: 10.15302/J-FEM-2014059

Abstract: a background in improving independent innovation capabilities and building a world-class petroleum researchinstitute, scientific innovation is the essence and basis of an innovative framework for a researchinventive problem solving (TRIZ) and combining it with CAI (computer aided innovation) technology, the ResearchThis article takes the example of the innovative practices of the Department of Petroleum Equipment in Research

Keywords： innovative capability     TRIZ theory     petroleum equipment     research institute     innovative system    

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A critical literature review of bioretention research for stormwater management in cold climate and futureresearch recommendations

Hannah Kratky, Zhan Li, Yijun Chen, Chengjin Wang, Xiangfei Li, Tong Yu

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 4, doi: 10.1007/s11783-017-0982-y

Abstract: bioretention is an effective stormwater management system, its design in cold climate needs further researchExisting cold climate research has shown that coarser media is required to prevent concrete frost fromResearch in these water quality aspects has been inconsistent and therefore requires further study.

Keywords： Bioretention     Cold climate     Low impact development     Stormwater    

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Engineering management: Global engineering research frontiers

Botao ZHONG, Luting QIU

Frontiers of Engineering Management 2020, Volume 7, Issue 1,   Pages 159-162 doi: 10.1007/s42524-020-0094-4

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Title Author Date Type Operation

Construction of a shared system-based real-world clinical research system

Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo

Journal Article

therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic

Journal Article

targeted therapy of gynecological malignant tumors: the development and challenge, from laboratory to clinic

Pengming SUN PhD, MD , Jalid SEHOULI PhD, MD , Lihui WEI BM ,

Journal Article

A Clinic Study of Testosterone Propionate Treatmemt in Patients With Unstable Angina

Ma Jianfang,Zeng Aiping,Xie Dehui,Qiu Fengying,Zhang Ning,Chen Hong

Journal Article

Clinical acupuncture research in the West

Xianze Meng, Shifen Xu, Lixing Lao

Journal Article

Do civil engineering fronts emerge from interdisciplinary research?

Journal Article

Integrating operations research into green logistics: A review

Journal Article

Numerical simulation and experimental research on the wheel brush sampling process of an asteroid sampler

Journal Article

The fundamental theory of traditional Chinese medicine and the consideration in its research strategy

Zhenji Li, Chunbo Xu

Journal Article

Recent progress in hydrodynamic characteristics research and application of annular centrifugal extractors

Journal Article

HIGHLIGHTS OF THE SPECIAL ISSUE ON “HORTICULTURE RESEARCH FOR GREEN AND SUSTAINABLE DEVELOPMENT”

Journal Article

CAPEES and FESE journal: Together to serve the environmental research community

Journal Article

The Effect of TRIZ on Research Institute Innovation

He Liu,Qing-hai Yang,Xu Jin

Journal Article

A critical literature review of bioretention research for stormwater management in cold climate and futureresearch recommendations

Hannah Kratky, Zhan Li, Yijun Chen, Chengjin Wang, Xiangfei Li, Tong Yu

Journal Article

Engineering management: Global engineering research frontiers

Botao ZHONG, Luting QIU

Journal Article